What is metabolic syndrome ? Metabolic syndrome is the name for a group of risk factors for heart disease, diabetes, and other health problems. You can ...
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What is metabolic syndrome ? Metabolic syndrome is the name for a group of risk factors for heart disease, diabetes, and other health problems. You can have just one risk factor, but people often have several of them together. When you have at least three of them, it is called metabolic syndrome . These risk factors include: A large waistline, also called abdominal obesity or "having an apple shape." Too much fat around the stomach is a greater risk factor for heart disease than too much fat in other parts of the body. Having a high triglyceride level. Triglycerides are a type of fat found in the blood. Having a low HDL cholesterol level. HDL is sometimes called the "good" cholesterol because it helps remove cholesterol from your arteries. Having high blood pressure. If your blood pressure stays high over time, it can damage your heart and lead to other health problems. Having a high fasting blood sugar. Mildly high blood sugar may be an early sign of diabetes. The more factors you have, the higher your risk for heart disease, diabetes, and stroke is. What causes metabolic syndrome ? Metabolic syndrome has several causes that act together: Overweight and obesity An inactive lifestyle Insulin resistance, a condition in which the body can't use insulin properly. Insulin is a hormone that helps move blood sugar into your cells to give them energy. Insulin resistance can lead to high blood sugar levels. Age - your risk goes up as get older Genetics - ethnicity and family history People who have metabolic syndrome often also have excessive blood clotting and inflammation throughout the body. Researchers don't know whether these conditions cause metabolic syndrome or worsen it. Who is at risk for metabolic syndrome ? The most important risk factors for metabolic syndrome are: Abdominal obesity (a large waistline) An inactive lifestyle Insulin resistance There are certain groups of people who have an increased risk of metabolic syndrome : Some racial and ethnic groups. Mexican Americans have the highest rate of metabolic syndrome , followed by White and Black people. People who have diabetes People who have a sibling or parent who has diabetes Women with polycystic ovary syndrome (PCOS) People who take medicines that cause weight gain or changes in blood pressure, blood cholesterol, and blood sugar levels What are the symptoms of metabolic syndrome ? Most of the metabolic risk factors have no obvious signs or symptoms, except for a large waistline. How is metabolic syndrome diagnosed? Your health care provider will diagnose metabolic syndrome based on the results of a physical exam and blood tests. You must have at least three of the risk factors to be diagnosed with metabolic syndrome : A large waistline, which means a waist measurement of 35 inches or more for women 40 inches or more for men A high triglyceride level, which is 150 mg/dL or higher A low HDL cholesterol level, which is Less than 50 mg/dL for women Less than 40 mg/dL for men High blood pressure, which is a reading of 130/85 mmHg or higher. A high fasting blood sugar, which is 100 mg/dL or higher What are the treatments for metabolic syndrome ? The most important treatment for metabolic syndrome is a heart-healthy lifestyle, which includes: A heart-healthy eating plan, which limits the amount of saturated and trans fats that you eat. It encourages you to choose a variety of nutritious foods, including fruits, vegetables, whole grains, and lean meats. Aiming for a healthy weight Managing stress Getting regular physical activity Quitting smoking (or not starting if you don't already smoke) If making lifestyle changes is not enough, you may need to take medicines. For example, you may need medicines to lower cholesterol or blood pressure. Can metabolic syndrome be prevented? The best way to prevent metabolic syndrome is through the heart-healthy lifestyle changes. NIH: National Heart, Lung, and Blood Institute Health topic information sourced from MedlinePlus, a service of the National Library of Medicine, National Institutes of Health.
Health topic information on this page is sourced from MedlinePlus, a service of the National Library of Medicine, National Institutes of Health. Visit medlineplus.gov for more information.
FDA-approved medications commonly prescribed for metabolic syndrome. This is not medical advice — a clinician decides which treatment fits your situation.
INDICATIONS AND USAGE Metformin hydrochloride tablets, USP are indicated as an adjunct to diet and exercise to improve glycemic control in adults and children with type 2 diabetes mellitus.
BLACK BOX WARNING: WARNINGS Lactic Acidosis: Lactic acidosis is a rare, but serious, metabolic complication that can occur due to metformin accumulation during treatment with metformin; when it occurs, it is fatal in approximately 50% of cases. Lactic acidosis may also occur in association with a…
INDICATIONS AND USAGE Metformin hydrochloride tablets, USP are indicated as an adjunct to diet and exercise to improve glycemic control in adults and children with type 2 diabetes mellitus.
BLACK BOX WARNING: WARNINGS Lactic Acidosis: Lactic acidosis is a rare, but serious, metabolic complication that can occur due to metformin accumulation during treatment with metformin; when it occurs, it is fatal in approximately 50% of cases. Lactic acidosis may also occur in association with a…
INDICATIONS AND USAGE Bupropion hydrochloride tablets are indicated for the treatment of major depressive disorder. A physician considering bupropion hydrochloride tablets for the management of a patient’s first episode of depression should be aware that the drug may cause generalized seizures in a dose-dependent manner with an approximate incidence of 0.4% (4/1,000). This incidence of seizures may exceed that of other marketed antidepressants by as much as 4-fold. This relative risk is only…
Recruiting trials that involve metabolic syndrome. Trial status changes often — always confirm with the trial coordinator before traveling.
No recruiting clinical trials are listed for this condition right now. Search ClinicalTrials.gov directly for the most current list.
A endocrinologist is typically the right starting point for metabolic syndrome.
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BLACK BOX WARNING: Suicidality and Antidepressant Drugs Use in Treating Psychiatric Disorders: Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD)…
INDICATIONS AND USAGE Bupropion hydrochloride tablets are indicated for the treatment of major depressive disorder. A physician considering bupropion hydrochloride tablets for the management of a patient’s first episode of depression should be aware that the drug may cause generalized seizures in a dose-dependent manner with an approximate incidence of 0.4% (4/1,000). This incidence of seizures may exceed that of other marketed antidepressants by as much as 4-fold. This relative risk is only…
BLACK BOX WARNING: Suicidality and Antidepressant Drugs Use in Treating Psychiatric Disorders: Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD)…