What is lupus? Lupus is a chronic (long-lasting) type of autoimmune disease.Autoimmune diseases happen when your immune system attacks healthy cells and ...
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What is lupus ? Lupus is a chronic (long-lasting) type of autoimmune disease.Autoimmune diseases happen when your immune system attacks healthy cells and tissues by mistake. This attack causes inflammation. It can also damage many parts of the body, including the joints, skin, kidneys, heart, lungs, and brain. There are several types of lupus : Systemic lupus erythematosus (SLE) is the most common type. It can be mild or severe and can affect many parts of the body. Cutaneous lupus affects the skin. It causes a rash or sores, usually after your skin is exposed to sunlight. The two major types of cutaneous lupus are discoid lupus and subacute cutaneous lupus . Drug-induced lupus is caused by a reaction to some medicines. The symptoms may start 3 to 6 months after starting the medicine. The symptoms usually go away when you stop taking the medicine. Neonatal lupus , which is rare, affects newborns. It is caused by certain antibodies that are passed from the pregnant parent to the baby. What causes lupus ? The cause of lupus is unknown. Researchers are studying what might cause or trigger the disease, such as: Genetics Environmental factors, such as viral infections, sunlight, certain medicines, and smoking Problems with the immune system Who is more likely to get lupus ? Anyone can get lupus , but women get it much more often than men. Lupus is more common in African Americans than in White people. It is also more common in people of American Indian and Asian descent. African American and Hispanic women are more likely to have severe forms of lupus . What are the symptoms of lupus ? Lupus can have many symptoms, and they differ from person to person. Some of the more common ones are: Arthritis, causing painful and swollen joints and morning stiffness Fever Fatigue or feeling tired often Red rashes, most often on the face (also called the "butterfly rash") Chest pain when taking a deep breath Hair loss Pale or purple fingers or toes, from cold and stress (Raynaud phenomenon) Sensitivity to the sun Swelling in legs or around eyes Mouth ulcers Swollen glands Headache and dizziness Confusion and memory problems Symptoms may come and go. When you are having symptoms, it is called a flare. Flares can range from mild to severe. New symptoms may appear at any time. What other problems can lupus cause? Lupus causes inflammation throughout your body. This can cause problems in your organs, including: Kidney damage ( lupus nephritis). Heart problems, including inflammation in the heart (myocarditis), heart valves, or lining of the heart muscle (pericarditis). Inflammation of blood vessels (vasculitis). Blood clots Inflammation of the tissue that surrounds the lungs (pleurisy). This can make it painful to breathe. Some people with lupus may be more likely to develop other conditions, such as coronary artery disease (CAD) and atherosclerosis. How is lupus diagnosed? There is no specific test for lupus , and it's often mistaken for other diseases that cause similar symptoms. So it may take a while to get a diagnosis. To find out if you have lupus , your health care provider: Will ask about your symptoms, medical history, and family health history Will do a complete physical exam May order blood tests, such as ANA (antinuclear antibody), antibodies, complete blood count, and complement tests May order other tests, such as urine tests May do biopsies: Skin biopsy (looking at skin samples under a microscope) Kidney biopsy (looking at tissue from your kidney under a microscope) What are the treatments for lupus ? There is no cure for lupus , but medicines and lifestyle changes can help control it. People with lupus often need to see different providers. You will most likely have a primary care provider and a rheumatologist (a doctor who specializes in diseases of the joints and muscles). Which other specialists you will depend on how lupus affects your body. For example, if lupus is damaging your heart or blood vessels, you would see a cardiologist (a doctor who specializes in heart diseases). Your primary care provider should coordinate care between all of your other providers and treat other problems as they come up. You and your primary care provider will develop a treatment plan to fit your needs. You will both review the plan often to make sure that it is working. You should report new symptoms to your provider right away so that your treatment plan can be changed, if needed. The goals of a treatment plan are to: Prevent flares Treat flares when they occur Reduce organ damage and other problems Improve your quality of life Treatments may include drugs to: Reduce fever, swelling, and pain Reduce inflammation in your body Prevent or reduce flares Reduce or prevent damage to joints Suppress (lower) the activity of your immune system Besides taking medicines for lupus , you may need to take medicines for problems that are related to lupus such as high cholesterol, high blood pressure, or infection. Alternative and complementary therapies are therapies that are not part of standard treatments. Some people try alternative and complementary therapies to improve their lupus symptoms. But research has not clearly shown whether these treatments may help or treat lupus . Talk to your provider before trying any new treatments. How can I cope with lupus ? It is important to take an active role in your treatment. It helps to learn more about lupus - being able to spot the warning signs of a flare can help you prevent the flare or make the symptoms less severe. It is also important to find ways to cope with the stress of having lupus . Exercising and finding ways to relax may make it easier for you to cope. A good support system can also help. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases Health topic information sourced from MedlinePlus, a service of the National Library of Medicine, National Institutes of Health.
Health topic information on this page is sourced from MedlinePlus, a service of the National Library of Medicine, National Institutes of Health. Visit medlineplus.gov for more information.
FDA-approved medications commonly prescribed for lupus. This is not medical advice — a clinician decides which treatment fits your situation.
INDICATIONS & USAGE Prednisone Tablets, USP are indicated in the following conditions: Endocrine Disorders Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice: synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy mineralocorticoid supplementation is of particular importance); congenital adrenal hyperplasia; hypercalcemia associated with cancer; nonsuppurative thyroiditis. Rheumatic Disorders As…
WARNINGS Rare instances of anaphylactoid reactions have occurred in patients receiving corticosteroid therapy (See ADVERSE REACTIONS: Allergic Reactions ). Increased dosage of rapidly acting corticosteroids is indicated in patients on corticosteroid therapy subjected to any unusual stress before,…
INDICATIONS AND USAGE MEDROL Tablets are indicated in the following conditions: 1. Endocrine Disorders Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy mineralocorticoid supplementation is of particular importance). Congenital adrenal hyperplasia Nonsuppurative thyroiditis Hypercalcemia associated with cancer 2. Rheumatic Disorders As adjunctive…
WARNINGS In patients on corticosteroid therapy subjected to unusual stress, increased dosage of rapidly acting corticosteroids before, during, and after the stressful situation is indicated. Corticosteroids may mask some signs of infection, and new infections may appear during their use.…
INDICATIONS AND USAGE Malaria Hydroxychloroquine sulfate tablets are indicated for the treatment of uncomplicated malaria due to P. falciparum, P. malariae, P. ovale, and P. vivax . Hydroxychloroquine sulfate tablets are indicated for the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported. Limitations of Use in Malaria Hydroxychloroquine sulfate tablets are not recommended for the treatment of complicated malaria. Hydroxychloroquine sulfate tablets are not…
Recruiting trials that involve lupus. Trial status changes often — always confirm with the trial coordinator before traveling.
No recruiting clinical trials are listed for this condition right now. Search ClinicalTrials.gov directly for the most current list.
A rheumatologist is typically the right starting point for lupus.
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WARNINGS Resistant strains of malaria: Hydroxychloroquine sulfate tablets are not effective against chloroquine-resistant strains of P. falciparum (see CLINICAL PHARMACOLOGY – Microbiology ). Ocular: Irreversible retinal damage has been observed in some patients who had received hydroxychloroquine…